Current views on the function of the lymphatic vasculature in health and disease
Identifieur interne : 005961 ( Main/Exploration ); précédent : 005960; suivant : 005962Current views on the function of the lymphatic vasculature in health and disease
Auteurs : Yingdi Wang [États-Unis] ; Guillermo Oliver [États-Unis]Source :
- Genes & Development [ 0890-9369 ] ; 2010.
Descripteurs français
- KwdFr :
- MESH :
- anatomopathologie : Maladies lymphatiques.
- embryologie : Vaisseaux lymphatiques.
- métabolisme : Vaisseaux lymphatiques.
- physiopathologie : Maladies lymphatiques, Vaisseaux lymphatiques.
- Animaux, Humains.
English descriptors
- KwdEn :
- MESH :
- embryology : Lymphatic Vessels.
- metabolism : Lymphatic Vessels.
- pathology : Lymphatic Diseases.
- physiopathology : Lymphatic Diseases, Lymphatic Vessels.
- Animals, Humans.
Abstract
The lymphatic vascular system is essential for lipid absorption, fluid homeostasis, and immune surveillance. Until recently, lymphatic vessel dysfunction had been associated with symptomatic pathologic conditions such as lymphedema. Work in the last few years had led to a better understanding of the functional roles of this vascular system in health and disease. Furthermore, recent work has also unraveled additional functional roles of the lymphatic vasculature in fat metabolism, obesity, inflammation, and the regulation of salt storage in hypertension. In this review, we summarize the functional roles of the lymphatic vasculature in health and disease.
Url:
DOI: 10.1101/gad.1955910
PubMed: 20889712
PubMed Central: 2947764
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en"><p>The lymphatic vascular system is essential for lipid absorption, fluid homeostasis, and immune surveillance. Until recently, lymphatic vessel dysfunction had been associated with symptomatic pathologic conditions such as lymphedema. Work in the last few years had led to a better understanding of the functional roles of this vascular system in health and disease. Furthermore, recent work has also unraveled additional functional roles of the lymphatic vasculature in fat metabolism, obesity, inflammation, and the regulation of salt storage in hypertension. In this review, we summarize the functional roles of the lymphatic vasculature in health and disease.</p>
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